An adaptive algorithm for n-body field expansions
Weinberg, Martin D.
1998-05-28
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94 records were found.
Oestrogenic hormones were originally isolated from ovarian
follicles and from placental tissue and were believed
to occur only in female animals. Laqueur et al. (1927}
observed, however, that extracts from human male urine
caused vaginal cornification in spayed mice. This discovery
of oestrogenic activity in urine from men was so unexpected,
that the authors thought it necessary to state that there
could be no doubt about the manliness of the subjects
studied. One of the oestrogenic substances in human male
urine was subsequently identified as oestrone (Dingemanse
et al., 1938), while later on oestradiol and oestriol were
also found to be present in urine from men (see: Diczfalusy
& Lauritzen, 1961). Since then, the occurrence of oestrogens
in the urine of male animals from several species has
been described (see: Velle, 1966). However...
The gradual increase in follicle stimulating hormone (FSH) concentrations
in women approaching menopause results from the depletion of the ovarian
follicular pool, a process referred to as 'ovarian ageing'. This study
investigates whether variable endogenous FSH concentrations, as have been
observed in normo-ovulatory young women, are related to menstrual cycle
characteristics, including predictors of ovarian ageing. Serum
concentrations of immunoreactive FSH, oestradiol, and inhibin-A and
inhibin-B were measured, and follicular growth was assessed by
transvaginal ultrasound throughout the follicular phase in 39 healthy
volunteers (20-35 years) with regular menstrual cycles. Median serum FSH
concentration on cycle day 3 was 5.1 IU/l (ran...
Aromatase inhibitors effectively delay epiphysial maturation in boys and improve testosterone levels in adult men Therefore, aromatase inhibitors may be used to increase adult height in boys with gonadotropin-independent precocious puberty, idiopathic short stature and constitutional delay of puberty. Long-term efficacy and safety of the use of aromatase inhibitors has not yet been established in males, however, and their routine use is therefore not yet recommended.
It has been suggested that the programming of the endocrine axes occurs
during critical phases of fetal development and will be affected by
intrauterine growth retardation. As a result, children born small for
gestational age (SGA) might have several hormonal disturbances. In later
life, one of the questions that might arise is: Do short children born SGA
have higher serum dehydroepiandrosterone sulfate (DHEAS) levels than their
peers? Therefore, we compared serum DHEAS levels of 181 short prepubertal
children aged 3-9 yr born SGA [birth length (SD score) below -2 for
gestational age] with a control group of 170 prepubertal age-matched,
normal-statured children born appropriate for gestational age (birth
length between -2 and +2 SD score). Because relatively high serum DHEAS
...
BACKGROUND: Anti-Mullerian hormone (AMH), produced by growing pre-antral
and early antral ovarian follicles, has been shown to be a useful marker
for ovarian ageing. Serum AMH concentrations are elevated during
reproductive life in anovulatory women, especially in those patients
exhibiting polycystic ovaries (PCO). The current study was designed to
investigate whether the decrease in AMH serum concentrations over time is
different comparing women with normogonadotrophic anovulation [World
Health Organization (WHO) group 2 (including polycystic ovary syndrome
(PCOS)] and normo-ovulatory controls. METHODS AND RESULTS: AMH serum
levels were assessed on two occasions in 98 patients suffering from WHO 2
anovulatory infertility as well as in 41 normo-ovulatory premenopausal
wo...
The objective of this study was to set up a superovulation protocol in
adult cyclic rats by using recombinant human follicle stimulating hormone
(rhFSH; Org32489). Good results were obtained by treatment with decreasing
doses of rhFSH (2.5 to 0.5 IU) during the dioestrus period. The number of
corpora lutea (CL) found in rats treated with this protocol was 43.5 +/-
3.4; this is more than three times the number in saline-treated control
rats (13.0 +/- 0.4). Fertilization of oocytes after superovulation was as
good as after normal ovulation in terms of number of 2-cell stage embryos
found 2 days after mating. The absolute number of implantations was twice
the number observed in saline-treated control rats (23.3 +/- 1.8 versus
10.6 +/- 0.5); therefore the number of implantations p...
