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Previous work has shown the positive correlation of echocardiographic right ventricular preejection period/right ventricular ejection time ratio (RPEP/RVET) with pulmonary vascular resistance and pulmonary arterial diastolic pressure obtained at cardiac catheterization. However, the correlation was insufficient to predict pulmonary arterial diastolic pressure or vascular resistance from a given RPEP/RVET ratio. In this study the RPEP/RVET ratio was compared with left ventricular preejection period/ejection time ratio (LVEP/LVET) in 25 patients undergoing cardiac catheterization, and a strong correlation was found between the ratio (RPEP/RVET)/(LPEP/LVET) = R/L and the ratio of pulmonary arteriolar resistance/systemic arteriolar resistance (PAR/RS), especially when R/L was correlated with log10PAR/RS (r = 0.902). A very high correlation...
The neonatal lupus syndrome consists of transient cutaneous lupus lesions or permanent congenital complete heart block (or hepatic fibrosis), or both, in infants born to mothers with systemic lupus erythematosus (SLE). The frequency of conduction abnormalities was examined in 86 offspring of 53 women affected by SLE. Electrocardiograms from the offspring demonstrated normal sinus rhythm in 84 of 86 offspring. The PR interval was normal for age (95th percentile (i.e., first-degree heart block) for both age and heart rate. The PR interval of the other 6 subjects with first-degree heart block for age or heart rate (>=95th percentile) was <=0.18 second. In contrast, using a rank assignment of PR intervals in relation to heart rate and age derived from published standards, grouped data indicated that heart rate adjusted for age was gr...
Total correction of tetralogy of Fallot was carried out in 215 patients from 1957 through mid-1967. Twenty-eight patients died during the period of hospitalization following the operation, and 5 died later. The operative mortality rate declined steadily throughout the period, reaching 2.2 per cent in the last 22 months. The major factors determining the outcome of surgical treatment were the age of the patient, the severity of the cardiac deformities, the beneficial effects of a prior systemic-pulmonary shunt, associated cardiac lesions, and the surgical technic.Total correction between the ages of 6 and 14 carries the most favorable prognosis. When young patients are severely cyanotic, it is better to establish a palliative systemic-pulmonary artery shunt, preferably by the Blalock-Taussig technic, and subsequently carry out the total...
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