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会期・会場: 2012年3月17日(土)10:00-17:00 : 神戸国際会議場メインホール ; 後援: 読売新聞社、(公財)京都大学教育研究振興財団、神戸大学
A dinuclear copper complex possessing an azobenzene backbone (Cu^[II]_[2]1) was synthesized and its affinity towards DNA was investigated and found to be dependent on the trans–cis isomeric forms. Upon exposure to UV light at 365 nm the trans form of the complex (Cu^[II]_[2]trans-1) underwent photoisomerization into the cis-isomer (Cu^[II]_[2]cis-1), which reverted to the original trans-form on exposure to visible light at 420 nm. Both thetrans and cis isomers exhibited moderate DNA cleavage activity toward plasmid duplex DNA in the presence of a reducing agent 3-mercaptopropionic acid (MPA) suggesting that the Cu^[I] species could activate molecular oxygen to form a reactive oxygen species in situ. Interestingly, the isomeric copper complexes showed different site-specificities in the oxidation of an oligodeoxynucleotide having single...
[Background]Ingestion of plant parts purportedly for their non-nutritive and/or bioactive properties has been widely reported across the animal kingdom. Many of these examples are viewed as behavioral strategies to maintain health by controlling the level of parasite infections. One such behavior is leaf swallowing, the folding and swallowing of whole leaves without chewing. Void of any nutritional benefit, defecation of the whole leaves is associated with the physical expulsion of intestinal parasites. Fecal samples of the Chinese lesser civet Viverricula indica were collected along a fixed transect line monthly for 17 months in the Fushan Experimental Forest, northeastern Taiwan. We inspected samples for the occurrence of undigested leaves and parasite worms to test the possible antiparasitic function of the behavior in this species....
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